Version: 1.0.0 | Published: 24 Mar 2026 | Updated: 35 days ago
Summary
Description:
Highly granular dataset of 1,000 cancer patients treated with checkpoint inhibitors, tracking acute healthcare visits, demographics, side effects, physiology, blood results, outpatient activity, consultations, prescriptions, treatments, and survival.
Access Tier:
Controlled
Contact Point:
Health Theme:
Cancer
Health Category:
Electronic Health Records (EHRs)
Number of Unique Individuals:
969
Documentation
Documentation:
A highly granular, medicines-focused dataset of approximately 1,000 patients over 3 years. Includes patient demographics & co-morbidities taken from ICD-10 & SNOMED-CT codes. Serial, structured data pertaining to acute care process (timings, readmissions, survival), primary diagnosis, presenting complaint, physiology readings (pulse, blood pressure, respiratory rate, oxygen saturations and others), extensive blood results (infection, inflammatory markers) and acuity markers such as AVPU Scale, NEWS2 score, SEWS score, imaging reports, consultation, therapy, referrals, complete documentation of all prescribed & administered treatments including fluids, blood products, procedures, information on outpatient admissions and survival outcomes following one year post discharge.
This medicines-focused dataset is an invaluable resource for researchers aiming to analyse and compare the effects of checkpoint inhibitors on patients. It offers an opportunity to understand treatment pathways and healthcare utilisation in this specific patient cohort. Dive into this rich data source to uncover new insights and contribute to the evolving field of cancer immunotherapy.
Geography: The West Midlands (WM) has a population of 6 million & includes a diverse ethnic & socio-economic mix. UHB is one of the largest NHS Trusts in England, providing direct acute services & specialist care across four hospital sites, with 2.2 million patient episodes per year, 2750 beds & > 120 ITU bed capacity. UHB runs a fully electronic healthcare record (EHR) (PICS; Birmingham Systems), a shared primary & secondary care record (Your Care Connected) & a patient portal “My Health”.
Data set availability: Data access is available via the PIONEER Hub for projects which will benefit the public or patients. This can be by developing a new understanding of disease, by providing insights into how to improve care, or by developing new models, tools, treatments, or care processes. Data access can be provided to NHS, academic, commercial, policy and third sector organisations. Applications from SMEs are welcome. There is a single data access process, with public oversight provided by our public review committee, the Data Trust Committee. Contact pioneer@uhb.nhs.uk or visit www.pioneerdatahub.co.uk for more details.
Available supplementary data: Matched controls; ambulance and community data. Unstructured data (images). We can provide the dataset in OMOP and other common data models and can build synthetic data to meet bespoke requirements.
Available supplementary support: Analytics, model build, validation & refinement; A.I. support. Data partner support for ETL (extract, transform & load) processes. Bespoke and “off the shelf” Trusted Research Environment (TRE) build and run. Consultancy with clinical, patient & end-user and purchaser access/ support. Support for regulatory requirements. Cohort discovery. Data-driven trials and “fast screen” services to assess population size
Coverage
Spatial
Spatial Coverage:
- United Kingdom
- England
- West Midlands
Temporal
Start Date:
17 January 2020
End Date:
08 October 2023
Frequency:
QUARTERLY
Date of Latest Release:
30 January 2024
Date of First Release:
08 October 2024
Temporal Aggregation:
1 - 10 Years
Provenance
Origin
Purpose:
Care
Collection Situation:
- Secondary care - Accident and Emergency
- Secondary care - In-patients
- Secondary care - Outpatients
Image Contrast:
Not stated
Method of Collection:
EPR
Access and Governance
Usage
Data Use Requirements:
Project specific restriction
Access
Jurisdiction:
England
Data Controller:
University Hospitals Birmingham NHS Foundation Trust
Delivery Lead Time:
1-2 months
Legal Basis:
General research use
Health Data Access Body:
This publication uses data from PIONEER, an ethically approved database and
analytical environment (East Midlands Derby Research Ethics 20/EM/0158)
Format and Standards
Language:
English
Format:
SQL
Conforms To:
LOCAL
Coding System:
- SNOMED CT
- ICD10
Data Distribution
Data Status:
Available
Distribution:
Trusted Research Environments (TRE) are built using Microsoft Azure services and
hosted in the UK to provide research teams a safe, secure and agile environment
which allows users to quickly analyse, interpret and form an enriched view of
primary care information through a range of integrated datasets. Health data
collated from multiple sources is ingested into a secure data lake which will
then allow subsets of data to be made available to research teams on approval of
a data request. Once approved a customer specific TRE is made available with a
standard set of leading analytical tools from Microsoft including Azure
Databricks, Azure Machine Learning, Azure SQL and Azure Synapse (for large-scale
data warehouses). Specific tools can be provided at an additional cost over the
standard platform data access charge and the PIONEER team will work with you to
determine your exact needs., www.pioneerdatahub.co.uk/data/data-services-costs/
Observations
Name
Population Type
Value
Description
Variable Measured
Unit Code
Observation Date
Number of Records
Minimum Typical Age
Maximum Typical Age
Persons
969
Count
22 October 2023
969
0
100
Origin
Name:
Data Catalogue